Publications

Metabolomic, lipidomic, and N-glycomic analyses of a human cell model of Krabbe disease reveal treatable deficits in glycosylation and serine-ceramide metabolism

Starosta R, Saeger H, ten Hoeve J, Kim SJ, Van Hove JLK, Jiang X, He M, Bennett N

bioRxiv preprint, August 2026

Genetic regulators of neuronal survival across metabolic environments

Bennett N, Soto-Muniz Y, Meng JX, Lee M, Yang J, Flanigan WR, Pico AR, Jain IH, Nakamura K

bioRxiv preprint, December 2025

Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy

Rius R, Bennett NK, Bhattacharya K, Riley LG, Yüksel Z, Formosa LE, Compton AG, Dale RC, Cowley MJ, Gayevskiy V, Al Tala SM, Almehery AA, Ryan MT, Thorburn DR, Nakamura K, Christodoulou J

Human Mutation, December 2022

Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function

Bennett NK, Nakaoka HJ, Laurent D, Okimoto RA, Sei Y, Horvai AE, Bivona TG, Ten Hoeve J, Graeber TG, Nakamura K, Nakamura JL

PLOS Biology, September 2022

Defining the ATPome reveals cross-optimization of metabolic pathways

Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K

Nature Communications, August 2020

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure

Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K

PLOS Biology, August 2018

Mapping the genetic landscape of human cells

Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA

Cell, August 2018

Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity

Bennett NK, Chmielowski R, Abdelhamid DS, Faig JJ, Francis N, Baum J, Pang ZP, Uhrich KE, Moghe PV

Biomaterials, December 2016

Self-assembling peptide nanofiber scaffolds for 3-D reprogramming and transplantation of human pluripotent stem cell-derived neurons

Francis NL, Bennett NK, Halikere A, Pang ZP, Moghe PV

ACS Biomaterials Science & Engineering, May 2016

Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP, Moghe PV

Nature Communications, March 2016